Riding the Economic Wave - Challenges and Opportunities

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Confirmed Speakers, Panelists, Chairs, and Moderators:

  • Hui Cai, Ph.D., M.B.A., Chair of Board, SABPA, BOD of SDCA, President and CEO, Inflexion BioPartners
  • Stephen M. Chang, Ph.D., CSO, Stemgent
  • Sheng Ding, Ph.D., Associate Professor, Department of Chemistry, The Scripps Research Institute
  • Eldora Ellison, Ph.D., Esq., Director, Sterne, Kessler, Goldstein & Fox PLLC
  • Xiangming Fang, M.D., Ph.D., President of SABPA SD, Sr. VP and CSO, eBioCenter Corporation
  • Jack Florio, MBA, Senior Vice President, Brinson Patrick Securities Corporation
  • Cheng Jin, M.D., Ph.D., Executive Director, Business Development, PharmaLegacy Laboratories
  • David Kabakoff, Ph.D., Executive-in-Residence, Sofinnova Ventures
  • Hua Zhu (David) Ke, Ph.D., Scientific Executive Director, Bone and Mineral Metabolism, Amgen Inc.
  • Hui Li, Ph.D., Vice Chair of Board, SABPA, Senior Principal Scientist, Pfizer Global Research & Development
  • Graham Lidgard, Ph.D., Senior Vice President of R&D, Nanogen
  • David Looney, M.D., Associate Professor IR, Medicine, UCSD Medical Center
  • Ronald B. Moss, M.D., Executive VP, Clinical Development & Medical Affairs, NexBio
  • K.C. Nicolaou, Ph.D. Professor, The Scripps Research Institute & UCSD
  • Sean M. Sullivan, Ph.D., Executive Director, Pharmaceutical Sciences, Vical, Inc.
  • Feng Tian, Ph.D., President of SDCAA, BOD of SABPA
  • Lloyd G. Tillman, Ph.D., Executive Director of Pharmaceutical Development, ISIS Pharmaceuticals, Inc.
  • Roger Tsien, Ph.D., Professor, UCSD, 2008 Nobel Prize Laureate for Chemistry
  • Randall E. Woods, President & CEO, Sequel Pharmaceuticals
  • Christina Yang, Ph.D., Senior VP,Clinical, Regulatory & Quality, GenProbe

Hui Cai, Ph.D., M.B.A., Chair of Board, SABPA, BOD of SDCA, President and CEO, Inflexion BioPartners

Dr. Hui Cai is Chairwoman of the Board at the Sino-American Biomedical and Pharmaceutical Professionals Association (SABPA, www.sabpa.org), Chairwoman of the San Diego Section of the American Chemical Society (ACS San Diego, www.sandiegoacs.org), and a former President of San Diego Chinese Association (SDCA, www.sdcausa.org). She was appointed by the Mayor of San Diego in 2002 and has served as a Commissioner at City of San Diego Science and Technology Commission.

Dr. Hui Cai is President & CEO of Inflexion BioPartners (www.inflexionbio.com), a professional consultancy that offers management and consulting services to help optimizing key resources along the biotech and pharmaceutical R&D value chain. Dr. Cai has a broad portfolio of expertise and solid track record in strategic initiatives aimed at maximizing organizational efficiency and efficacy. She is also a recognized leader in fostering government, academia, and industry relations, both locally and internationally. Prior to Inflexion BioPartners, she was Vice President of Corporate Development at HUYA Bioscience International, where she was involved in strategic planning, strategic partnership, cross-Pacific operation, international sourcing of drug candidates, and portfolio management.

Prior to that, Dr. Cai had nearly ten years of pharmaceutical research and development experience at Johnson & Johnson Pharmaceutical Research and Development, co-leading multiple small molecule drug discovery and development programs. She is a co-author and co-inventor to over 40 scientific publications and issued or pending patents.

Dr. Cai received her BS and MS from Peking University, PhD in Chemistry from The Scripps Research Institute, and MBA from UCSD Rady School of Management as a recipient of the distinguished DLA Piper - Athena FlexMBA Scholarship.
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Stephen M. Chang, Ph.D., CSO, Stemgent

Dr. Stephen Chang is Chief Scientific Officer at Stemgent. Prior to that he has served as a director of the MultiCell Technologies since June 2004, became president of MultiCell Technologies in February 2005, and was appointed chief executive officer (CEO) in May 2006. Dr. Chang is also president of MCT Rhode Island Corp. and Xenogenics Corporation, and president, chief financial officer (CFO), treasurer, and director of MCTI, a partially-owned subsidiary of the Company. Dr. Chang is president of CURES, a coalition of patient advocates, biotechnology companies, pharmaceutical companies, and venture capitalists dedicated to ensuring the safety, research, and development of innovative life saving medications. Dr. Chang is also on the Board of BIOCOM, San Diego’s premier life sciences organization. Dr. Chang was chief science officer (CSO) and vice president of Canji Inc./Schering Plough Research Institute in San Diego from 1998 to 2004. He earned his doctoral degree in biological chemistry, molecular biology, and biochemistry from the University of California, Irvine.
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Sheng Ding, Professor, Department of Chemistry, The Scripps Research Institute

Dr. Sheng Ding is currently Associate Professor in the Department of Chemistry at The Scripps Research Institute in La Jolla, USA. He obtained his B.S. in chemistry with honors from Caltech in 1999, and a Ph.D. in chemistry from Scripps in 2003. Dr. Ding’s lab has been developing and integrating chemical and functional genomics tools to study stem cell biology and regeneration, with a focus on applying high throughput cellular screening approaches to identify and further characterize novel small molecules that can control various cell fate/function. Ding is also a cofounder of Fate Therapeutics and Stemgent.
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Eldora Ellison, Ph.D., Esq., Director, Sterne, Kessler, Goldstein & Fox PLLC

Eldora Ellison, Ph.D., Esq. is a Director in the law firm of Sterne, Kessler, Goldstein & Fox PLLC. In addition to holding a law degree from Georgetown University Law Center, Dr. Ellison holds a Ph.D. in Biochemistry, Molecular and Cell Biology from Cornell University. Dr. Ellison's practice focuses on patent issues in the life sciences, and includes counseling clients on intellectual property strategy; evaluating patent portfolios; representing clients in patent litigations and interferences; licensing; conducting validity, non-infringement, and freedom-to-operate analyses; preparing and prosecuting patent applications; resolving complex inventorship disputes; carrying out due diligence investigations; and client counseling regarding FDA/ANDA practice. Dr. Ellison has represented a variety of types of organizations, including large corporations, small start-up companies, and not-for-profit organizations.
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Xiangming Fang, M.D., Ph.D., President of SABPA SD, Sr. VP and CSO, eBioCenter Corporation

Dr. Fang is Co-Founder, Senior Vice President and Chief Scientific Officer at eBioCenter Corporation (www.ebiocenter.com), an internet-based company providing marketing and information services in the fields of biopharma and life sciences.

Dr. Fang has 26 years of experience in biomedical research and product development, including 16 years of biotech industry experience and 10 years of management experience. She has strong scientific background with integrated knowledge in medicine, molecular and cell biology, protein chemistry and immunology. Previously as the Senior Vice President and Chief Scientific Officer at GenWay Biotech, she is responsible for new technology and product development and production, as well as customer support and partnership coordination. Prior to GenWay, Dr. Fang served at GenStar Therapeutics, initially as the Director of the Cancer Program and the Director of Preclinical Studies, then as Vice President, Hemophilia and Vector Development. She was responsible for managing preclinical studies of hemophilia and cancer programs, providing technical support to the GMP manufacturing of clinical materials and to Pre-IND and IND submission. In her previous employment, as a Research Scientist at Baxter Healthcare Corporation, Dr. Fang was the co-inventor of the oncolytic dual-viral system for cancer gene therapy. Prior to Baxter, as a Sr. Scientist at GeneMedicine, Inc., Dr. Fang led the effort to develop a non-viral vector system for gene therapy of hemophilia B.

Dr. Fang obtained her M.D. degree from Zhejiang University Medical School and Ph.D. in Molecular Biology from the University of Alabama. She completed her postdoctoral studies at the University of Texas, MD Anderson Cancer Center.

Dr. Xiangming Fang is the current President of Sino-American Biomedical and Pharmaceutical Professional Association, San Diego Chapter (SABPA, San Diego). She has served as BOD of SABPA for 6 years.
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Jack Florio, MBA, Senior Vice President, Brinson Patrick Securities Corporation

Jack J. Florio is Senior Vice President with Brinson Patrick Securities Corporation, a New York based investment banking boutique serving the equity capital raising needs of small cap to Fortune 500 publicly traded companies. He is also Vice President, Marketing and Communications and an active investor with San Diego Tech Coast Angels, the largest angel investor network in the United States.

Previously Jack had a 30-year career with Eli Lilly and Company where he held a number of senior management positions in the US and abroad. In many of these roles, Jack was involved with the development and management of various advisory boards.

Jack arrived in San Diego in April 2001 and has taken on both full and part time senior management roles in seven different biotech and medical device companies in the US, Europe, and China. These included In Jet Digital Aerosols, Biota, Opticon, Infacare, Aegis Therapeutics, Vital Therapies, and Hepawash. Jack was working heavily in China with Vital Therapies focused on commercialization, partnering, and capital acquisition. More recently Jack was President of InterPharmaLinkUSA, a global transaction oriented management consulting firm focused on partnering and M&A in the pharmaceutical and biotech industries where he remains as an advisor.

Jack also is very active in the community in a variety of roles including working with CONNECT on Springboard panels and other programs as well as several BIOCOM committees. Jack is currently on the boards of the San Diego Chapter of the American Liver Foundation and the San Diego Venture Group.

Mr. Florio received his BS in Pharmaceutical Sciences from Columbia University and his MBA from New York University.
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Cheng Jin, Executive Director, Business Development, PharmaLegacy Laboratories Laboratories

Dr. Cheng Jin is the Executive Director, Business Development of PharmaLegacy Laboratories, a Shanghai-based CRO company focusing on providing preclinical specialty pharmacology services.

Prior to joining PharmaLegacy Laboratories, Dr. Jin served as CSO of Imagene Co. Ltd, Seoul, Korea. He led P43 project for anti-cancer, autoimmune and cosmetic applications and managed international collaborations. Prior to joining Imagene Co. Ltd, he was the Assistant Director of Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences (CAS), and managed the overall responsibility of global business development. He successfully initiated and led the success in $50 million long-term collaboration deal with Astra-Zeneca. Dr. Jin received 2004 Wang Kuan Cheng Research Fellowship Award.

Dr. Jin gained over more than 10 years of drug discovery and development experience at local bio-pharmaceutical companies in US as a researcher (Res. Scientist, Sr. Res. Scientist, and Lead Scientist) and Director. Dr. Jin authored more than 30 articles published in scientific journals. Dr. Jin obtained his M.D. in Clinical Medicine, China Medical University, China and Ph.D. in Molecular Biology at Showa University, Tokyo, Japan.
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David Kabakoff, Executive-in-Residence, Sofinnova Ventures

David Kabakoff, Ph.D., joined Sofinnova Ventures as an Executive-in-Residence in 2007. David has 30 years of experience leading technology and product development programs in the pharmaceutical, biopharmaceutical, and drug delivery fields. He currently serves as Chairman of Trius Therapeutics and Chairman of Amplimmune, Inc. He is also a Director of InterMune, Inc.; Avalon Pharmaceuticals, Inc.; and Alylix, Inc. Dr. Kabakoff also serves as a Board Observer at Intellikine and Anza Therapeutics.

David co-founded Salmedix, Inc., a developer of cancer drug treatments, and served as the company’s Chairman and Chief Executive Officer. In June 2005, David negotiated the acquisition of Salmedix by Cephalon, Inc. David also held the positions of Executive Vice President, President and Chief Executive Officer of Spiros Development Corp. while at Dura Pharmaceuticals, a specialty respiratory pharmaceutical and pulmonary drug delivery company. Earlier, David was also employed as Chief Executive Officer of Corvas International and held senior executive positions with Hybritech, Inc.

David received his Ph.D. from Yale University and his B.A. from Case Western Reserve University.
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Hua Zhu (David) Ke, Scientific Executive Director, Bone and Mineral Metabolism, Amgen Inc.; Adjunct professor, University of Utah School of Medicine, Salt Lake City, Utah

Dr. Ke's primary research interests include bone biology, osteoporosis and orthopedic related research. Specifically, his research areas include selective estrogen receptor modulators (SERMs), estrogen receptor alpha and beta and their regulation on bone metabolism, androgen and selective androgen receptor modulator, prostaglandin E receptors and their skeletal effects, OPG/RANK/RANKL and their regulations on bone resorption, etc. Most recently he and his group have focused on the research related to osteoblasts regulation, specifically the sclerostin pathway and its role on bone formation. He has authored or co-authored approximately 90 scientific papers in the peer-review scientific journals, and is an inventor or co-inventor of more than 30 patents. Dr. Ke finished his post-doc training in University of Utah, and became a research scientist in Pfizer Global Research and Development in 1992. In 2005, he joined Amgen bone research group. Currently Dr. Ke is a Scientific Executive Director in Amgen and serves as the head of Amgen bone and orthopedic research group. In addition, he is an adjunct professor at the University of Utah School of Medicine, Salt Lake City, Utah.
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Christopher LeMasters, CBO, Tragara Pharmaceuticals, Inc.

Mr. LeMasters is co-founder and Chief Business Officer of Tragara Pharmaceuticals, where he oversees the operational and financial functions of the company. At Tragara, he completed the negotiation with Daiichi-Sankyo for the company’s founding license to Capoxigem™ (apricoxib, TG01). He also negotiated the company’s world-wide license to SB1317 (TG02) from S*BIO Pte Ltd of Singapore. Previously, Mr. LeMasters was a co-founder and Chief Business Officer of Cabrellis Pharmaceuticals, where he negotiated the company’s $104 million acquisition by Pharmion Corporation in 2006. He also served as Vice President, Business Development of Conforma Therapeutics where he was responsible for the in-licensing of Amrubicin from Dainippon Sumitomo and for negotiating the $250 million acquisition by Biogen Idec. Mr. LeMasters earlier worked for six years in Corporate Business Development at Eli Lilly and Company in Indianapolis. In that role, he was responsible for the successful negotiation of numerous partnerships and licenses across diverse therapeutic areas. Mr. LeMasters was also a management consultant with Coopers & Lybrand Consulting in Chicago for four years, where he led strategy consulting projects for Fortune 500 clients. He specialized in turn-around and profit improvement strategy and implementation. Mr. LeMasters began his business career as an operational auditor with Owens Corning Fiberglas in Toledo, Ohio, where he led formal assessments of internal organizations and manufacturing/distribution operations. Mr. LeMasters has a B.A. in Finance from Indiana University and an M.B.A. with honors from the University of Chicago, and is a Co-Founder and Board Member of Aarden Pharmaceuticals of Indianapolis and San Diego.
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Hui Li, Ph.D. Vice Chair of Board, SABPA, Senior Principal Scientist, Pfizer Global Research & Development

Dr. Hui Li is a senior principal scientist at Pfizer Global Research & Development, La Jolla Laboratories. Over the past 9 years, he has led research efforts in multiple disease areas including anti-viral, diabetes oncology and ophthalmology. He is a co-inventor of Filibuvir (PF-00868554), a Hepatitis C Virus polymerase inhibitor currently in phase II clinical trial. Dr. Li obtained his B.S degree from Peking University and Ph.D in organic chemistry from University of California, San Diego. There he worked under the guidance of Professor K. C. Nicolaou on new synthetic technology development and the total synthesis of glycopeptide antibiotic Vancomycin.

Dr. Li is a founding member of the Sino-American Biomedical & Pharmaceutical Association (SABPA) in 2002 and is currently the vice chairman of SABPA board. He also served as SABPA (San Diego) president from 2006 to 2008 and established the Alliance of Chinese-American Biotechnology and Pharmaceutical Associations with other organizations across the US.
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Graham Lidgard, Ph.D., Senior Vice President of R&D, Nanogen

Dr. Graham Lidgard joined Nanogen in January 2003 with over 28 years of experience in the Clinical Diagnostics industry. Nanogen has two contracts with the Center for Disease Control and Prevention (CDC) for the development of cllinical diagnostic assays for influnza detection and subtyping in a POC setting with a rapid immunoassay and in a laboratory setting with highly sensitive multiplexed real time PCR. He was previously Vice President of Research and Development at Gen-Probe where he led the R&D organization to develop DNA probe products for blood screening and STD's as well as the fully automated probe system, TIGRIS. Prior to Gen-Probe he was a co-founder of Matritech Inc., a cancer diagnostics company in Massachusetts and held several positions with Corning Medical/Ciba Corning in program management, business development, marketing, technology acquisition and product development capacities. Dr. Lidgard received his B.S. and Ph.D. in Biological Chemistry from the University of Manchester.
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David Looney, M.D., Associate Professor, Medicine, UCSD Medical Center

Dr. Looney graduated from the University of Missouri School of Medicine in 1979 and performed his internship and residency training at Letterman Army Medical Center in San Francisco. His infectious disease fellowship was done at the Brook Army Medical Center in San Antonio, TX, and the the Texas State Chest Hospital and Hansen's Disease Center in San Antonio. He completed training in Tropical Medicine at the Walter Reed Army Insitute of Research, and did postdoctoral training in the laboratory of Dr. Flossie Wong-Staal at the NCI Laboratory of Tumor Cell Biology.

Since coming to UCSD in 1989, Dr. Looney has conducted both basic and clinical research involving HIV vaccine, Gene Therapy of HIV infection, Kaposi's Sarcoma, and investigations into the role of small RNAs in transcriptional silencing and HIV replication. He current is leader of the Center for AIDS Research Molecular Biology Core, which provides support to HIV-investigators and developmental projects.
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Ronald B. Moss, M.D., Executive VP, Clinical Development & Medical Affairs, NexBio

Ron brings to NexBio 22 years of research and clinical experience, including 15 years of pharmaceutical drug development experience ranging from Phase 1 to NDA, and extensive expertise in clinical, regulatory and quality affairs. He previously worked at several biopharmaceutical companies in various capacities including Rhone Poulenc Rorer (now Aventis), Immune Response Corporation, Telos and Merck, where he was Senior Director of Worldwide Regulatory Affairs for Vaccines/Biologics in the Merck Research Laboratories division. Most recently, he was Vice President of Clinical Development at Vical, Inc., a publicly-traded company, where he guided the clinical development of various biological products for emerging infectious diseases, including U.S. Government-funded development of a pre-pandemic influenza vaccine. Ron earned his M.D. degree at the Chicago Medical School, having graduated Phi Beta Kappa with a bachelor's degree from the State University of New York at Stony Brook (SUNY). He completed his residency in Pediatrics at SUNY, followed by a fellowship at the National Institute of Allergy and Infectious Disease, where he was Clinical Associate in Allergy and Clinical Immunology. Ron is Board-certified in both Pediatrics and Allergy & Immunology.
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K.C. Nicolaou, Chairman, Department of Chemistry, The Scripps Research Institute

Dr. K.C. Nicolaou was born on July 5, 1946 in Cyprus, where he grew up and went to school until the age of 18. In 1964, he emigrated to England where he spent two years learning English and preparing to enter the university. His advanced studies in chemistry were carried out at the University of London (B.Sc., 1969, Bedford College, First Class Honors; Ph.D. 1972, University College, with Professors F. Sondheimer and P.J. Garratt). In 1972, he crossed the Atlantic to the United States and completed postdoctoral appointments at Columbia University (1972-1973, Professor T.J. Katz) and Harvard University (1973-1976, Professor E.J. Corey) after which he joined the faculty at the University of Pennsylvania, where he rose through the ranks to become the Rhodes-Thompson Professor of Chemistry. In 1989, he accepted joint appointments at the University of California, San Diego, where he is Professor of Chemistry, and The Scripps Research Institute, where he is the Chairman of the Department of Chemistry and holds the Darlene Shiley Chair in Chemistry and the Aline. W. and L. Skaggs Professorship in Chemical Biology. For his scientific work, Professor Nicolaou has received numerous awards and honors, including the Humboldt Foundation US Senior Scientist Prize (Germany, 1987), the A.C. Cope Scholar Award, American Chemical Society (1987), the Award for Creative Work in Synthetic Organic Chemistry, American Chemical Society (1993), the Dr. Paul Janssen Prize for Creativity in Organic Synthesis, Janssen Research Foundation (1994), the Rhone-Poulenc Medal, Royal Society of Chemistry (U.K., 1995), the William H. Nichols Medal, New York Section-American Chemical Society (1996), the Inhoffen Medal, Gesellschaft fur Biotechnologische Forschung mbH (GBF) (Germany, 1996), the Ernest Guenther Award in the Chemistry of Natural Products, American Chemical Society (1996), the Chemical Pioneer Award, American Institute of Chemists (1996), the Linus Pauling Award, Oregon, Portland, Puget Sound Sections-American Chemical Society (1996), the Decoration of the Order of the Commander of Honor Medal (bestowed by the President of Greece, 1998), the Esselen Award for Chemistry in the Public Interest, American Chemical Society (1998), the Yamada Prize (Japan, 1999), the first Aspirin Prize for Solidarity through Chemistry (Spain, 1999), the Max Tishler Lecture Prize, Harvard University (2000), the Paul Karrer Gold Medal, Universitat Zurich (Switzerland, 2000), the Centenary Medal, Royal Society of Chemistry (U.K., 2000-2001), the Ernst Schering Prize, Ernst Schering Research Foundation (Germany, 2001), the Nagoya Gold Medal of Organic Chemistry, Nagoya University (Japan, 2001), Tetrahedron Prize for Creativity in Organic Chemistry (2002), the ACS Nobel Laureate Signature Award for Graduate Education in Chemistry (2003), the Aristeio Bodossaki Prize (2004), the ACS A.C. Cope Award (2005) Auburn Section-American Chemical Society Auburn-G. M. Kosolapoff Award (2006), the Burkardt-Helferich Prize (2006), the ISHC Senior Award in Heterocyclic Chemistry (2007), the August-Wilhelm-von-Hofmann-Denkmünze Award (2008), and the Chandler Medal, Columbia University (2008).

Nicolaou is a Member of the New York Academy of Sciences (1987), Fellow of the American Academy of Arts and Sciences (1993), Member of the National Academy of Sciences (USA, 1996), Fellow of the American Association for the Advancement of Science (1999), Foreign Member, Academy of Athens (Greece, 2001), and holds 12 honorary degrees from universities around the world.

He is the author or co-author of almost 700 scientific articles, reviews, and book chapters, over 60 patents, and 4 books, including the popular Classics in Total Synthesis co-authored with his student Erik J. Sorensen (1996 VCH), Classics in Total Synthesis II co-authored with his student Scott A. Snyder (2003, Wiley-VCH), and Molecules That Changed the World, co-authored with his research associate T. Montangon (2008, Wiley-VCH). His dedication to chemical education is evidenced by his training of more than 400 graduate students and postdoctoral fellows.
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Sean M. Sullivan, Executive Director, Pharmaceutical Sciences, Vical, Inc.

Dr. Sean Sullivan is Executive Director, Pharmaceutical Sciences at Vical, Inc. He is in charge of Pharmaceutical Development and Scale up of Vical’s Genetic Vaccine Products. Prior to joiningVical, Dr. Sullivan was a tenured Associate Professor in the Department of Pharmaceutics, College of Pharmacy, and University of Florida for 7 years. Dr. Sullivan also had a joint appointment with the Shands Cancer Institute. Prior to joining the University, he was in the biotechnology industry for 14 years developing liposome and polymer based nucleic acid delivery systems for the treatment of infectious disease (HIV, HSV and Hepatitis), arthritis and cancer. These delivery systems were for topical and systemic administration of antisense DNA, ribozymes and plasmid DNA. He has authored 40 publications and is an inventor on 19 patents. He has served as an Adhoc member of several NIH study sections and has been on the editorial board for Human Gene Therapy and Pharmaceutical Research.
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Feng Tian, Ph.D. President of SDCA, BOD of SABPA

Dr. Feng Tian was a Scientific Investigator at Metabasis Therapeutics, Inc., where he focuses on the discovery of novel small molecule drugs targeting liver diseases and metabolic diseases such as diabetes, hyperlipidemia, and liver fibrosis. After obtaining his B.S. and M.S. degrees from Peking University in China, Feng went to Michigan State University and acquired his Ph.D. degree in Organic Chemistry. Then he moved to San Diego and completed his postdoctoral research at the Scripps Research Institute. Feng served as the program co-chair of Annual Symposium on Biopharmaceuticals in 2005 and 2007. Currently, he is a board member of SABPA and the President of San Diego Chinese American Association, where he focuses on promoting volunteerism and fostering leadership among its members.
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Lloyd G. Tillman, Executive Director of Pharmaceutical Development, ISIS Pharmaceuticals, Inc.

Dr. Lloyd Tillman is Executive Director of Pharmaceutical Development at Isis Pharmaceuticals, Inc., Carlsbad, CA. He is responsible for formulation research and development of antisense drugs. Beyond enabling new formulations for antisense based therapeutics, he manages development activities for preclinical and clinical supplies and for product registration. While at Isis, he has published several peer-reviewed manuscripts focusing on oligonucleotide formulations. He also lectures courses on Drug Dosage Form Design and Delivery Systems and on Concepts of Pharmacy Practice at the UCSD Skaggs School of Pharmacy and Pharmaceutical Sciences.

Prior to joining Isis in 1997, Dr. Tillman worked at the FDA overseeing the Product Quality Research Laboratory within CDER. His group focused to derive science-based data to support SUPAC and Biopharmaceutics Drug Classification System initiatives and other regulatory guidance’s. Previous to the FDA he worked on oral solid dosage forms at Burroughs Wellcome Co. where he managed the pharmaceutical product development of several NCE's into clinical trials and in two cases (MEPRON and VALTREX) into production and onto the market.
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Roger Tsien, Ph.D., Professor, UCSD; Howard Hughes Medical Institute; 2008 Nobel Prize Laureate for Chemistry

Roger Y. Tsien, Ph.D., was born in New York City in 1952 and received his A.B. in Chemistry and Physics summa cum laude from Harvard College in 1972. A Marshall Scholarship then took him to the Physiological Laboratory at the University of Cambridge, where he received his Ph.D. in 1977 and remained as a Research Fellow until 1981. He then became an Assistant, Associate, then full Professor in the Dept. of Physiology-Anatomy at the University of California, Berkeley. In 1989 he moved to the University of California, San Diego, where he is an Investigator of the Howard Hughes Medical Institute and Professor in the Depts. of Pharmacology and of Chemistry & Biochemistry.

Tsien is renowned for revolutionizing the fields of cell biology and neurobiology by allowing scientists to peer inside living cells and watch the behavior of molecules in real time. He is well-known for developing colorful dyes, such as Fura-2, to track the movement of calcium within cells and has genetically modified organisms to produce the molecules that make jellyfish and corals glow, creating fluorescent colors in a dazzling variety of hues. These multicolored fluorescent proteins are used by scientists to track where and when certain genes are expressed in cells or in whole organisms.

In 2004, Tsien was awarded the Wolf Prize in Medicine "for his seminal contribution to the design and biological application of novel fluorescent and photolabile molecules to analyze and perturb cell signal transduction." He was elected to the Institute of Medicine in 1995, the National Academy of Sciences in 1998, and the Royal Academy in 2006.

In 2008, Tsien shared the Nobel Prize in Chemistry with Osamu Shimomura and Martin Chalfie for "the green fluorescent protein: discovery, expression and development."

Roger Y. Tsien has received several honors and awards in his life, including:

  • Lamport Prize, New York Academy of Sciences(1986)
  • Javits Neuroscience Investigator Award, National Institute of Neurological Disorders and Stroke(1989)
  • Young Scientist Award, Passano Foundation(1991)
  • W. Alden Spencer Award in Neurobiology, Columbia University (1991)
  • Artois-Baillet-Latour Health Prize, Belgium (1995)
  • Gairdner Foundation International Award, Canada (1995)
  • Basic Research Prize, American Heart Association (1995)
  • Elected to Institute of Medicine (1995)
  • Elected to American Academy of Arts and Sciences (1998)
  • Elected to the National Academy of Sciences (1998)
  • Award for Innovation in High Throughput Screening, Society for Biomolecular Screening (1998)
  • Herbert Sober Lectureship, American Society for Biochemistry and Molecular Biology (2000)
  • Pearse Prize, Royal Microscopical Society (2000)
  • ACS Award for Creative Invention, American Chemical Society (2002)
  • Christian B. Anfinsen Award, Protein Society (2002)
  • Heineken Prize for Biochemistry and Biophysics, Royal Netherlands Academy of Sciences (2002)
  • Max Delbrück Medal, Max Delbrück Centrum für Molekulare Medizin, Berlin (2002)
  • Wolf Prize in Medicine, Israel (2004)
  • Keio Medical Science Prize, Japan (2004)
  • Perl Prize in Neuroscience, U. North Carolina(2005)
  • J.Allyn Taylor International Prize in Medicine, Robarts Institute in Canada(2005)
  • ABRF Award, Association Biomolecular Resource Facilities(2006)
  • Lewis S. Rosenstiel Award for Distinguished Work in the Basic Medical Sciences, Brandeis University(2006)
  • Fellow of the Royal Society, UK (2006)
  • Nobel Prize in Chemistry, Sweden(2008)
  • E.B. Wilson Medal, American Society for Cell Biology(2008) .
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Randall E. Woods, President & CEO, Sequel Pharmaceuticals

Randall E. Woods is the President and Chief Executive Officer and a member of the Board of Directors of Sequel Pharmaceuticals. Mr. Woods served in the same capacity at NovaCardia prior to its acquisition by Merck & Co. Mr. Woods brings to Sequel 36 years of experience in the biotech/pharmaceutical arena. Mr. Woods served nearly eight years as the Chief Executive Officer of Corvas International, Inc., a publicly traded biopharmaceutical company focused on cardiovascular disease and cancer. Prior to Corvas, Mr. Woods was President of Boehringer Mannheim’s US Pharmaceutical operations and spent over 20 years at Eli Lilly & Company in sales and marketing positions. Mr. Woods served as the chairman for the advisory board of the University of California, San Diego’s Sulpizio Family Cardiovascular Center and is the Chairman of the board of Directors for BIOCOM, a life science industry association in Southern California. He also serves on the Board of Arena Pharmaceuticals. Mr. Woods received his Bachelor Degree in Biology and Chemistry and a Masters Degree in Marketing.
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Christina Yang, Senior Vice President, Clinical, Regulatory & Quality, GenProbe

Dr. Yang joined the Company in April 2007 as Vice President, Clinical, Regulatory and Quality. Dr. Yang brings over fifteen years experience in regulatory and clinical affairs, quality assurance and quality control. Most recently, Dr. Yang served as Vice President, Quality and Regulatory Affairs of Focus Diagnostics, owned by Quest Diagnostics, consisting of laboratory services, clinical trial and IVD production units with focus on infectious disease. Immediately prior, Dr. Yang held a variety of management positions in R&D, quality systems, diagnostic operations, and technical manufacturing. From 1987 to 1995, Dr. Yang served in quality control, biochemistry and allergy, and organic chemistry management positions at Diagnostic Products Corporation in Los Angeles. She has a B.S. in Biology from National Taiwan Normal University, Taipei, Taiwan and a Ph.D in Zoology from Iowa State University, Iowa. Dr. Yang is a Regulatory Affairs Certified (RAC), ISO9000 certified lead auditor as well as a Certified Quality Auditor (CQA).
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